Salvage reirradiation for local failure of prostate cancer after curative radiation therapy: Association of rectal toxicity with dose distribution and normal-tissue complication probability models
نویسندگان
چکیده
منابع مشابه
Reirradiation of Prostate Cancer Local Failures After Previous Curative Radiation Therapy: Long-Term Outcome and Tolerance.
PURPOSE To evaluate the safety, feasibility, side-effect profile, and proof of concept of external beam radiation therapy (EBRT) with or without a brachytherapy (BT) boost for salvage of exclusive local failure after primary EBRT for prostate cancer. METHODS AND MATERIALS Fourteen patients with presumed exclusive local recurrence after primary EBRT with or without BT were considered eligible ...
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Introduction: Chemoradiation is a well-established protocol for management of localized esophageal cancer. However, some early and late toxicities are associated with this therapy. Plan evaluation in term of normal tissue complication probability (NTCP) may help clinicians to tailor this therapy more individually. Given the variety of present radiobiological models, the choice...
متن کاملSalvage brachytherapy in prostate local recurrence after radiation therapy: predicting factors for control and toxicity
PURPOSE To evaluate efficacy and toxicity after salvage brachytherapy (BT) in prostate local recurrence after radiation therapy. METHODS AND MATERIALS Between 1993 and 2007, we retrospectively analyzed 56 consecutively patients (pts) undergoing salvage brachytherapy. After local biopsy-proven recurrence, pts received 145 Gy LDR-BT (37 pts, 66%) or HDR-BT (19 pts, 34%) in different dose levels...
متن کاملMultivariate normal tissue complication probability modeling of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer
BACKGROUND The risk of radio-induced gastrointestinal (GI) complications is affected by several factors other than the dose to the rectum such as patient characteristics, hormonal or antihypertensive therapy, and acute rectal toxicity. Purpose of this work is to study clinical and dosimetric parameters impacting on late GI toxicity after prostate external beam radiotherapy (RT) and to establish...
متن کاملTreatment failure after primary and salvage therapy for prostate cancer.
BACKGROUND The authors report the likelihood of treatment failure and the outcomes after salvage therapy among men with prostate cancer who initially either received external-beam radiation therapy (EBRT) or underwent radical prostatectomy (RP). METHODS Using a national disease registry, the Cancer of the Prostate Strategic Urological Research Endeavor (CaPSURE) database, 5277 men with prosta...
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ژورنال
عنوان ژورنال: Advances in Radiation Oncology
سال: 2018
ISSN: 2452-1094
DOI: 10.1016/j.adro.2018.06.001